Anemia, a lack of red blood cells, can cause fatigue, pale skin, weakness, dizziness, headache and more. The pale white color is due to virtually no blood flow to the skin. While the condition itself causes no pain or discomfort, it can be an indicator of more serious health concerns. Also steroid creams and gels are used in many cases as the first option for treatment of inverse psoriasis. A grainy appearance to the skin, caused by tiny fluid-filled blisters just under the skin called “vesicles.” Weeping when the blisters burst, either by themselves or because of scratching, and the fluid oozes on to the surface of the skin. Medication: Insulin, anti-diabetic medication like metformin ... slow healing of cuts, and itchy skin. Why? Crusts or scabs that form when the fluid dries. Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary tract obstruction. However, there are a number of other factors affecting the skin's thickness. The cause of Raynaud's phenomenon is unknown, although abnormal nerve control of blood-vessel diameter and nerve sensitivity to cold are suspected of being … There are medications, e.g., cortisone, aspirin, warfarin, and heparin which cause the rash to appear as a side effect. Long-term vision loss can also be caused by diabetic retinopathy. Talk to your doctor about the risks of receiving methotrexate injection for your condition. These medications work to lower fever by causing blood vessels to dilate so heat is lost through the skin, and this same mechanism may lead to sweating. Other causes continued Allergy symptoms: Hives, rashes and swelling Hives, also known as Urticaria, are an outbreak of swollen, pale red bumps, patches, or welts on the skin that appear suddenly. Multiple sclerosis. They work by reducing the excessive firing of neurons that happens in a seizure. First, severe vasoconstriction reduces blood flow to the skin of the affected areas, causing the skin surface to feel cold to touch and to have a white color. Certain medications may also cause red palms, especially in people with impaired liver function. Topically applied medications (e.g., flea and tick spot-on products) will sometimes irritate the skin and cause hair loss, redness, flaking and/or itching. It's a common problem in older adults. This eases swelling and itching and will protect your eyes and face. Bilirubin is usually transported to the liver where it combines with bile. Sufferers of anemia, low blood pressure, leukemia, hypertension, hypopituitarism, and chronic heart issues may all have paleness that can last a long time. Hair follicles can also become highly prominent and visible. Dry skin may be more at risk for developing dermatitis, or an inflammation of the skin. A rash involves a change in the color and texture of your skin. As such, the paleness may come and go with them. Psoriasis is thought to be an immune system problem that causes the skin to regenerate at faster than normal rates. Opioids . Because the skin around the eye is relatively thin and transparent compared to skin in other parts of the body, the black and blue color of a bruised eye may seem darker and more intense than bruises elsewhere. Often there are patches of redness that is first noticed. Motion sickness. Opioids such as morphine, hydrocodone, and Dilaudid are a well-known cause of excessive sweating. Not everyone with liver disease will develop white nails, for example -- and not everyone with white nails has liver disease. This gives urine its pale yellow color and stool its darker brownish color. Discolored lips can be due to a number of reasons, from harmless staining to severe underlying conditions. Causes. Raynaud's phenomenon is a type of vascular disease characterized by a pale to blue to red sequence of color changes of the digits, most commonly after exposure to cold. While the medication may work, it may also cause the skin to appear yellow. There is no way to prevent rheumatoid arthritis skin issues. Deficiencies. People who are experiencing skin rashes or shingles may also have tactile sensitivity. ; Raynaud's phenomenon occurs because of spasm of blood vessels. Some of the most common causes of eyelid discoloration are: Bruising: Usually after a trauma to the eye area Hormone changes caused by cyclic changes, thyroid, pregnancy, menopause or illness Prescription medications can cause eyelid color change. Doctors will try different therapies to manage all RA symptoms. Use lotions or creams, avoid taking hot showers, and use gentle soaps to help keep your skin soft and moist. Following are some of the most common causes why you notice sudden paleness in your skin color. This forms the rash. A doctor can prescribe medications that will tone down the immune reaction in the skin. In the most common type of psoriasis, known as plaque psoriasis, this rapid turnover of cells results in scales and red patches. Pressure ulcers can be caused by skin changes, loss of the fat layer, reduced activity, poor nutrition, and illnesses. Anemia, a lack of red blood cells, can cause fatigue, pale skin, weakness, dizziness, headache and more. Methotrexate may cause very serious, life-threatening side effects. Diagnosis. Another potential cause is infiltration – when the fluid leaks into the tissue around the vein. Iron deficiency; Iron deficiency is the most familiar deficiency in the whole of the United States. Your doctor will review your medical history, your current symptoms and any medications … An illness may cause nail changes in some people but not in others. For the case of medications, these are the medications that normally cause an allergic reaction to occur beneath your skin surface. Many drugs can cause cutaneous (skin) ... Anticonvulsant drugs, also known as antiepileptic or antiseizure drugs, are a diverse group of medications that are commonly used in the treatment of epilepsy and seizures, and less commonly for other conditions such as trigeminal neuralgia and bipolar disorder. Bruises, flat collections of blood (purpura), and raised collections of blood may form after even a minor injury. 1. It can cause cramping pain in the leg muscles, especially during exercise. Hyperhidrosis. For example, a person may use a topical form of tetracycline for the treatment of a skin infection. If you have pale or clay-colored stool, it could be something you ate or a medication you are taking. Heat exhaustion causes intense thirst, heavy sweating, pale, cool, and moist skin, muscle cramps, and more. Rubbing or pulling on the skin can cause skin tears. There are some causes of pale skin that can result in long-lasting paleness. Lichen sclerosus is an uncommon condition that causes thin, patchy white spots on the skin in both males and females. In some cases, pale stools may be caused by certain over-the-counter medications or substances used in X-ray procedures, such as barium. Motion sickness is a feeling of queasiness or nausea caused by moving in a car, bus, boat, or plane. 4. Just what causes the immune system to malfunction isn't entirely clear. Bacterial and viral infections within your body can cause your skin to break out in spots as well. Anemia. If medications are the cause of RA skin symptoms, medication replacement or reduction may help prevent or reduce skin symptoms. As you advance in years, the layers of your skin simply thin and become more fragile. ... Alternatively, some cases may cause skin changes that appear like wart-like lesions. The Mayo Clinic characterizes thin, fragile skin as skin that easily tears or breaks. Some common medications that cause dry skin are diuretics like hydrochlorothiazide or furosemide, Retin-A, cholesterol medication like … Multiple sclerosis is a disease of the nervous system causing difficulties with balance, speech, and movement. Anemia. It often appears in the genital areas. If your lips turn blue and you're having trouble breathing or … Prolonged high blood glucose can cause glucose absorption in the lens of the eye, which leads to changes in its shape , resulting in vision changes. The immune cells of the skin can also produce rashes when they react to invading germs—like bacteria, fungi and viruses. Children with eczema often have dry, scaly skin. Medication dosing errors Fortunately, however, the medication does not permanently discolor the skin. Due to fever. Palmar erythema — also known as red palm disease — is characterized by reddish, blotchy skin around the palms and fingers. Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and whites of the eyes due to high bilirubin levels. Causes of Pale Skin. Pale stools may also be accompanied by jaundice, a yellowing of the skin and whites of the eyes (sclerae) caused by a buildup of bilirubin in the body. There are many underlying causes for a pale skin. While this is a less common complication, it can cause numbness, tingling, and even loss of function in the limb. Blood collects under the skin, and causes black or blue discoloration in the eyelids and around the eye socket. Meds that relieve pain are valuable tools for doctors and patients. If the change is due to medication, it should not be a cause for worry. If narrowing is severe, there may be pain at rest, cold toes and feet, pale or bluish skin and hair loss on the legs. Researchers believe both genetics and environmental factors play a role. Telltale Signs of Palmar Erythema. Itching skin, also called pruritus, can have many causes, such as a yeast infection, dry skin, or poor blood flow. Pale skin, or skin with a yellowish hue; Shortness of breath; Fast resting heart rate (over 100 beats per minute) 1.2 Idiopathic Thrombocytopenic Purpura (ITP) Excessive bruising and bleeding—bruises often appearing from internal bleeding—are the most common purpura symptoms of ITP. Some symptoms are difficulty maintaining body temperature and paleness due to anemia. There are certain medications that cause dry skin by reducing the stratum corneum's water levels, making it porous and leaky. It often appears in the genital areas. Usually washing the area with mild soap and cool water and some time is all that is needed to for the skin to return to normal, then avoid using the product that caused the reaction in the future. Fragile blood vessels can break easily. The paleness may go away when the root cause is taken care of, but some of these causes are reoccurring. The skin then typically becomes a purplish-blue color (called acrocyanosis), as a reduced flow of blood through the skin returns. The skin may also become cold, pale and dry. Medication side effects include nausea, vomiting, stomach upset, weakness, dizziness, seizures, and more. This causes increased sensitivity for a short time. Moisturizers will also prevent itching due to dry skin. If an infiltration is severe enough, it can cause compartment syndrome and lead to nerve damage. Apart from excessive pressure and an injury, the rash can also be caused by certain medications. You should only receive methotrexate injection to treat life-threatening cancer, or certain other conditions that are very severe and that cannot be treated with other medications. A Word From Verywell . Yellow skin caused by topical treatments can usually be cleared up with soap. 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